MALT1 (MALT-Lymphoma Marker) Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityMALT1 (MALT-Lymphoma Marker)
Clone[SPM578]
Host SpeciesMouse
Reactive Specieshuman
IsotypeIgG1, kappa
Formatunconjugated
Size0.02 mg (With BSA & Azide at 0.2mg/ml), 0.1 mg (With BSA & Azide at 0.2mg/ml), 0.1 mg (Without BSA & Azide at 1mg/ml)
Concentrationn/a
ApplicationsFlow Cytometry (FC/FACS), Immunofluorescence (IF), Western Blot (WB), Immunohistochemistry (IHC) Formalin
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DescriptionSpecificity: Mucosa associated lymphoid tissue lymphoma translocation gene 1 (MALT1) is found in extranodal low-grade B cell lymphomas. MALT1 encodes two Ig-like C2-type domains and fuses with an API2 gene, which is highly expressed in adult lymphoid tissue. The translocation of this MALT1 gene, which maps to human chromosome 18q21, and the apoptosis-inhibiting API2 gene results in an increased development of MALT lymphomas and apoptosis inhibition. Sites at which this API2-MALT1 (11;18)(q21;q21) translocation commonly occurs are within human lung and kidney tissue. MALT lymphoma expresses nuclear Bcl10, which mediates the oligomerization and activation of a MALT1 caspase-like domain. MALT1 mRNA is found in pre-B cells, mature B cells and p
ImmunogenImmunogen: Human MALT1 recombinant fragment (aa701-808)
Other Names[Caspase-like protein, MALT lymphoma-associated translocation, MLT1, Mucosa-associated lymphoid tissue lymphoma translocation protein 1, Paracaspase], [MALT1; MALT1; MLT; MLT1; IMD12; PCASP1; MLT]
Gene, Accession #[MALT1], Gene ID: 10892, NCBI: NP_006776.1, UniProt: Q9UDY8
Catalog #MBS438138
Price$190, $340, $340
Order / More InfoMALT1 (MALT-Lymphoma Marker) Antibody from MYBIOSOURCE INC.
Product Specific ReferencesYe H et. al. J Pathol 2005; 205: 293-301
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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