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Antigenic Specificity | SOCS7 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | antigen affinity purified |
Size | 0.1 mL |
Concentration | 1.1 mg/ml |
Applications | Immunohistochemistry (IHC) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | The antibody detects endogenous levels of total SOCS7 protein. The protein as regulator signaling cascades probably through protein ubiquitination and/or sequestration. It plays an important role in insulin signaling and glucose homeostasis through IRS1 ubiquitination and subsequent proteasomal degradation. Inhibits also prolactin, growth hormone and leptin signaling by preventing STAT3 and STAT5 activation, sequestering them in the cytoplasm and reducing their binding to DNA. |
Immunogen | Immunogen Type: Peptide Immunogen Description: Synthetic peptide corresponding to residues near the N terminal of human suppressor of cytokine signaling 7 |
Other Names | [NAP4; NCKAP4] |
Gene, Accession # | [SOCS7], Gene ID: 30837, NCBI: NP_055413.1, UniProt: O14512 |
Catalog # | MBS9412214 |
Price | $255 |
Order / More Info | SOCS7 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |