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Antigenic Specificity | MED17 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | affinity purified |
Size | 0.1 mL |
Concentration | n/a |
Applications | Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | The activation of gene transcription is a multistep process that is triggered by factors that recognize transcriptional enhancer sites in DNA. These factors work with co-activators to direct transcriptional initiation by the RNA polymerase II apparatus. The protein encoded by this gene is a subunit of the CRSP (cofactor required for SP1 activation) complex, which, along with TFIID, is required for efficient activation by SP1. This protein is also a component of other multisubunit complexes e.g. thyroid hormone receptor-(TR-) associated proteins which interact with TR and facilitate TR function on DNA templates in conjunction with initiation factors and cofactors. |
Immunogen | Immunogen: Recombinant protein of human MED17 (NP 004259.3). |
Other Names | [mediator of RNA polymerase II transcription subunit 17; Mediator of RNA polymerase II transcription subunit 17; mediator of RNA polymerase II transcription subunit 17; mediator complex subunit 17; Activator-recruited cofactor 77 kDa component; ARC77; Cofactor required for Sp1 transcriptional activation subunit 6; CRSP complex subunit 6; Mediator complex subunit 17; Thyroid hormone receptor-associated protein complex 80 kDa component; Trap80; Transcriptional coactivator CRSP77; Vitamin D3 receptor-interacting protein complex 80 kDa component] |
Gene, Accession # | [MED17], Gene ID: 9440, NCBI: NP_004259.3, UniProt: Q9NVC6 |
Catalog # | MBS8574086 |
Price | $280 |
Order / More Info | MED17 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |