P62/SQSTM1 Antibody from MYBIOSOURCE INC.
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| Antigenic Specificity | P62/SQSTM1 |
| Clone | monoclonal |
| Host Species | Mouse |
| Reactive Species | human |
| Isotype | IgG2a |
| Format | Protein A purified |
| Size | 0.06 mL, 0.12 mL, 0.2 mL |
| Concentration | 1mg/mL |
| Applications | ELISA (EIA), Western Blot (WB), Immunofluorescence (IF) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Sequestosome 1 (SQSTM1/p62) is a multifunctional adaptor protein implicated in selective autophagy, cell signaling pathways, and tumorigenesis. p62 has been implicated in shuttling ubiquitinated and sometimes aggregated proteins for autophagic degradation. As a autophagy-specific substrate, p62 is degraded during the autophagic process, which makes intracellular level of p62 as a marker for autophagy flux. p62 is at the cross-roads of several signaling pathways including Ras/ Raf/ MAPK and NFkappaB and plays important role in cancer. p62 is a component of inclusion bodies/ protein aggregates found in human diseases, including Huntington's disease, Alzheimer's disease, Parkinson's disease in the brain, and nephropathic cystinosis in kidney ( |
| Immunogen | Immunogen: P62/SQSTM1 fusion protein ag13131 |
| Other Names | [A170; EBIAP; ORCA; OSIL; p60; P62; P62;SQSTM1; p62B; PDB3; sequestosome 1; SQSTM1; Ubiquitin binding protein p62; ZIP3] |
| Gene, Accession # | [P62/SQSTM1], Gene ID: 8878, NCBI: NP_001135770.1, UniProt: Q13501 |
| Catalog # | MBS2540223 |
| Price | $220, $290, $435 |
| Order / More Info | P62/SQSTM1 Antibody from MYBIOSOURCE INC. |
| Product Specific References | n/a |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
sales@mybiosource.com
http://www.MyBioSource.com
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