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Antigenic Specificity | MAPK14 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | immunogen affinity purified |
Size | 0.1 mL |
Concentration | 1.0 mg/ml |
Applications | Western Blot (WB), Immunohistochemistry (IHC), Immunofluorescence (IF) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | The antibody detects endogenous level of total MAPK14 protein. p38 MAP kinase (MAPK), also called RK (1) or CSBP (2), is the mammalian orthologue of the yeast HOG kinase that participates in a signaling cascade controlling cellular responses to cytokines and stress (1-4). Four isoforms of p38 MAPK, p38a, b, g (also known as Erk6 or SAPK3), and d (also known as SAPK4) have been identified. Similar to the SAPK/JNK pathway, p38 MAPK is activated by a variety of cellular stresses including osmotic shock, inflammatory cytokines, lipopolysaccharide (LPS), UV light, and growth factors (1-5). MKK3, MKK6, and SEK activate p38 MAPK by phosphorylation at Thr180 and Tyr182. Activated p38 MAPK has been shown to phosphorylate and activate MAPKAP kinase 2 |
Immunogen | Immunogen Type: Peptide Immunogen Description: A synthetic peptide of human MAPK14. |
Other Names | [MAPK14; CSBP; CSBP1; CSBP2; CSPB1] |
Gene, Accession # | [MAPK14], Gene ID: 1432, NCBI: NP_001306.1, UniProt: Q16539 |
Catalog # | MBS9413259 |
Price | $255 |
Order / More Info | MAPK14 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |