Edit |   |
---|---|
Antigenic Specificity | PARK7/DJ1 Picoband |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | mouse, rat |
Isotype | n/a |
Format | immunogen affinity purified |
Size | 0.1 mg |
Concentration | Add 0.2ml of distilled water will yield a concentration of 500ug/ml. |
Applications | ELISA (EIA), Immunohistochemistry (IHC), Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Description: Parkinson disease (autosomal recessive, early onset) 7, also known as DJ1, is a protein which in humans is encoded by the PARK7 gene. PARK7 belongs to the peptidase C56 family of proteins. PARK7 is mapped to chromosome 1p36. It acts as a positive regulator of androgen receptor-dependent transcription. It is also involved in tumorigenesis and in maintaining mitochondrial homeostasis. This gene may also function as a redox-sensitive chaperone, as a sensor foroxidative stress, and it apparently protects neurons against oxidative stress and cell death. It has been found that PARK7 mutations that impair transcriptional coactivator function can render dopaminergic neurons vulnerable to apoptosis and may contribute to the pathogenesis |
Immunogen | Immunogen: E Coli-derived mouse PARK7/DJ1 recombinant protein (Position: A2-D189). Subcellular Localization: Cell membrane Tissue Specificity: Expressed in erythroblasts and in mature red blood cells from peripheral blood (at protein level). |
Other Names | [Protein DJ-1; DJ-1; Parkinson disease protein 7 homolog; Protein deglycase DJ-1] |
Gene, Accession # | [PARK7/DJ1], Gene ID: 57320, NCBI: NP_065594.2, UniProt: Q99LX0 |
Catalog # | MBS1750476 |
Price | $315 |
Order / More Info | PARK7/DJ1 Picoband Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |