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Antigenic Specificity | Granzyme B |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | affinity purified |
Size | 0.1 mL |
Concentration | n/a |
Applications | Immunohistochemistry (IHC), Immunocytochemistry (ICC), Immunofluorescence (IF), Immunoprecipitation (IP) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | This enzyme is necessary for target cell lysis in cell-mediated immune responses. It cleaves after Asp. Seems to be linked to an activation cascade of caspases (aspartate-specific cysteine proteases) responsible for apoptosis execution. Cleaves caspase-3,-7,-9 and 10 to give rise to active enzymes mediating apoptosis. |
Immunogen | Immunogen: A synthesized peptide derived from human Granzyme B |
Other Names | [Granzyme B; Cathepsin G-like 1; CTSGL1; Lymphocyte protease; Fragmentin-2; Granzyme-2; Human lymphocyte protein; SECT; CGL1; CSPB; CTLA1, GRB] |
Gene, Accession # | [GZMB], Gene ID: 3002, NCBI: NP_004122.2, UniProt: P10144 |
Catalog # | MBS8543244 |
Price | $280 |
Order / More Info | Granzyme B Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |