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Antigenic Specificity | HRAS (C-term), 146-176 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse (predicted reactivity: chicken, rat) |
Isotype | n/a |
Format | purified |
Size | 0.08 mL, 0.4 mL |
Concentration | vial concentration: 2 |
Applications | Western Blot (WB), ELISA (EIA), Immunofluorescence (IF) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | This HRAS antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 146-176 amino acids from the C-terminal region of human HRAS. This gene belongs to the Ras oncogene family, whosemembers are related to the transforming genes of mammalian sarcomaretroviruses. The products encoded by these genes function insignal transduction pathways. These proteins can bind GTP and GDP,and they have intrinsic GTPase activity. This protein undergoes acontinuous cycle of de- and re-palmitoylation, which regulates itsrapid exchange between the plasma membrane and the Golgi apparatus.Mutations in this gene cause Costello syndrome, a diseasecharacterized by increased growth at the prenatal stag |
Immunogen | n/a |
Other Names | [GTPase HRas; H-Ras-1; Ha-Ras; Transforming protein p21; c-H-ras; p21ras; GTPase HRas; N-terminally processed; HRAS; HRAS1] |
Gene, Accession # | [HRAS], Gene ID: 3265, NCBI: NP_001123914.1, UniProt: P01112 |
Catalog # | MBS9209161 |
Price | $165, $370 |
Order / More Info | HRAS (C-term), 146-176 Antibody from MYBIOSOURCE INC. |
Product Specific References | Ma, Z., et al. Oncogene 29(41):5559-5567(2010) van Engen-van Grunsven, A.C., et al. Am. J. Surg. Pathol. 34(10):1436-1441(2010) Li, H., et al. Oncogene 29(36):5083-5094(2010) Kwack, K.B., et al. Korean J Gastroenterol 56(2):78-82(2010) Amosenko, F.A., et al. Genetika 46(5):700-708(2010) |