AKT1 Antibody from MYBIOSOURCE INC.
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| Edit | |
|---|---|
| Antigenic Specificity | AKT1 |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | mouse, rat |
| Isotype | n/a |
| Format | immunogen affinity purified |
| Size | 0.1 mg |
| Concentration | n/a |
| Applications | Western Blot (WB) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Rabbit IgG polyclonal antibody for RAC-alpha serine/threonine-protein kinase(Akt1) detection. Background: RAC-alpha serine/threonine-protein kinase is an enzyme that in humans is encoded by the AKT1 gene. The serine-threonine protein kinase encoded by the AKT1 gene is catalytically inactive in serum-starved primary and immortalized fibroblasts. AKT1 and the related AKT2 are activated by platelet-derived growth factor. The activation is rapid and specific, and it is abrogated by mutations in the pleckstrin homology domain of AKT1. It was shown that the activation occurs through phosphatidylinositol 3-kinase. In the developing nervous system AKT is a critical mediator of growth factor-induced neuronal survival. Survival factors can suppress a |
| Immunogen | Immunogen: A synthetic peptide corresponding to a sequence at the C-terminus of mouse AKT1 (397-421aa EDAKEIMQHRFFANIVWQDVYEKKL), different from the related human sequence by two amino acids, and identical to the related rat sequence. |
| Other Names | [AKT 1; AKT1; AKT; PKB; PKB-ALPHA; PRKBA; Protein Kinase B Alpha; Protein kinase B; RAC Alpha; RAC; RAC-PK-alpha; P31749; RAC-alpha serine/threonine-protein kinase; thymoma viral proto-oncogene 1], [Akt1; Akt1; Akt; PKB; Rac; LTR-akt; PKB/Akt; PKBalpha; Akt; Rac; PKB; PKB alpha] |
| Gene, Accession # | [Akt1], Gene ID: 11651, NCBI: NP_001159366.1, UniProt: P31750 |
| Catalog # | MBS178579 |
| Price | $280 |
| Order / More Info | AKT1 Antibody from MYBIOSOURCE INC. |
| Product Specific References | 1. Entrez Gene: AKT1 v-akt murine thymoma viral oncogene homolog 1.2. Lindhurst MJ, Sapp JC, Teer JK, Johnston JJ, Finn EM, Peters K, Turner J, Cannons JL, Bick D, Blakemore L, Blumhorst C, Brockmann K, Calder P, Cherman N, Deardorff MA, Everman DB, Golas G, Greenstein RM, Kato BM, Keppler-Noreuil KM, Kuznetsov SA, Miyamoto RT, Newman K, Ng D, O'Brien K, Rothenberg S, Schwartzentruber DJ, Singhal V, Tirabosco R, Upton J, Wientroub S, Zackai EH, Hoag K, Whitewood-Neal T, Robey PG, Schwartzberg PL, Darling TN, Tosi LL, Mullikin JC, Biesecker LG (2011). A mosaic activating mutation in AKT1 associated with the Proteus syndrome. N. Engl. J. Med. 365 (7): 611-9. |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
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San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
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