GAP43 Antibody from MYBIOSOURCE INC.
Search, find, compare suppliers for anti-GAP43 antibody, protein, ELISA kits.
| Edit | |
|---|---|
| Antigenic Specificity | GAP43 |
| Clone | polyclonal |
| Host Species | Mouse |
| Reactive Species | human, mouse, rat |
| Isotype | n/a |
| Format | unconjugated |
| Size | 0.1 mL |
| Concentration | n/a |
| Applications | Immunocytochemistry (ICC), Immunofluorescence (IF), Western Blot (WB) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | GAP-43 (growth associated protein 43 kDa; also known as neuromodulin) is a 24 kDa, neuron growth cone-associated member of the neuromodulin family. Apparently due to its tertiary structure, it runs anomalously at 43 kDa on SDS-polyacrylamide gel. Rat GAP-43 is a 226 amino acid (aa) protein that contains an N-terminal lipid binding motif, an 11 aa IQ domain (IQ:Ile-Gln-X-Ser-etc) (aa 38 - 48), and a C-terminus with four potential serine phosphorylation sites. The molecule may utilize the IQ domain to bind calmodulin. Protein kinase C-mediated phosphorylation of the Serine at 41 within this site inhibits this interaction. Unphosphorylated, calmodulin-bound GAP-43 is always associated with neurite retraction, while S41 phosphorylated GAP-43 st |
| Immunogen | Immunogen: C-terminal peptide of rat and mouse GAP43, which is KEDPEADQEHA, to which an N-terminal Cysteine residue was added to allow chemical coupling to Keyhole Limpet Hemocyanin carrier protein. |
| Other Names | [GAP43; Neuromodulin; Axonal membrane protein GAP-43; Calmodulin-binding protein P-57; Growth-associated protein 43], [GAP43] |
| Gene, Accession # | [GAP43], NCBI: AAO60065.1 |
| Catalog # | MBS555041 |
| Price | $380 |
| Order / More Info | GAP43 Antibody from MYBIOSOURCE INC. |
| Product Specific References | n/a |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
sales@mybiosource.com
http://www.MyBioSource.com
Profile of MYBIOSOURCE INC.
Return to Antibodies