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Antigenic Specificity | SMYD2 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | peroxidase (HRP) conjugate |
Size | 0.05 mg, 0.1 mg |
Concentration | n/a |
Applications | ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Protein-lysine N-methyltransferase that methylates both histones and non-histone proteins, including p53/TP53 and RB1. Specifically methylates histone H3 'Lys-4' (H3K4me) and dimethylates histone H3 'Lys-36' (H3K36me2). Shows even higher methyltransferase activity on p53/TP53. Monomethylates 'Lys-370' of p53/TP53, leading to decreased DNA-binding activity and subsequent transcriptional regulation activity of p53/TP53. Monomethylates RB1 at 'Lys-860'. |
Immunogen | Immunogen: Recombinant human N-lysine methyltransferase SMYD2 protein |
Other Names | [N-lysine methyltransferase SMYD2; HSKM-B; Histone methyltransferase SMYD2; Lysine N-methyltransferase 3C; SET and MYND domain-containing p; SMYD2; KMT3C] |
Gene, Accession # | [SMYD2], Gene ID: 56950, NCBI: NP_064582.2, UniProt: Q9NRG4 |
Catalog # | MBS7044433 |
Price | $160, $235 |
Order / More Info | SMYD2 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |