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Antigenic Specificity | CKIP-1 (N-term), 49-77 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human (predicted reactivity: bovine) |
Isotype | n/a |
Format | purified |
Size | 0.08 mL, 0.4 mL |
Concentration | n/a |
Applications | Western Blot (WB), ELISA (EIA), Immunohistochemistry - Paraffin (IHC-P), Flow Cytometry (FC/FACS) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | This CKIP-1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 49-77 amino acids from the N-terminal region of human CKIP-1. CKIP-1 plays a role in the regulation of the actin cytoskeleton through its interactions with actin capping protein (CP). This protein may function to target CK2 to the plasma membrane thereby serving as an adapter to facilitate the phosphorylation of CP by protein kinase 2 (CK2). It appears to target ATM to the plasma membrane and appears to also inhibit tumor cell growth by inhibiting AKT-mediated cell-survival. Also implicated in PI3K-regulated muscle differentiation, the regulation of AP-1 activity (plasma membrane bound AP-1 regulator that translocates to the nucleus) and |
Immunogen | n/a |
Other Names | [Pleckstrin homology domain-containing family O member 1; PH domain-containing family O member 1; C-Jun-binding protein; JBP; Casein kinase 2-interacting protein 1; CK2-interacting protein 1; CKIP-1; Osteoclast maturation-associated gene 120 protein; PLEKHO1; CKIP1; OC120] |
Gene, Accession # | [PLEKHO1], Gene ID: 51177, NCBI: NP_057358.2, UniProt: Q53GL0 |
Catalog # | MBS9207531 |
Price | $165, $370 |
Order / More Info | CKIP-1 (N-term), 49-77 Antibody from MYBIOSOURCE INC. |
Product Specific References | Barrios-Rodiles,M., et.al., Science 307 (5715), 1621-1625 (2005) |