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Antigenic Specificity | NLK |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | antigen affinity purified |
Size | 0.06 mL, 0.12 mL, 0.2 mL |
Concentration | 1mg/mL |
Applications | Western Blot (WB), Immunohistochemistry (IHC) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | The activation of signal transduction pathways by growth factors, hormones and neurotransmitters is mediated through two closely related MAP kinases, p44 and p42, designated extracellular-signal related kinase 1 (ERK 1) and ERK 2, respectively. ERK proteins are regulated by dual phosphorylation at specific tyrosine and threonine sites mapping within a characteristic Thr-Glu-Tyr motif. Phosphorylation at both Thr-183 and Tyr-185 is required for full enzymatic activation. In response to activation, MAP kinases phosphorylate downstream components on serine and threonine (5, 6). Nlk, or nemo-like kinase, is a murine homolog of the Drosophila nemo (nmo) gene. Nlk and Nmo have sequence homology to both the ERK MAP kinases and the cyclin dependent |
Immunogen | Immunogen: Recombinant protein of human NLK Observed Molecular Weight: 58kDa |
Other Names | [NLK; LAK1; Protein LAK1; DKFZp761G1211; FLJ21033] |
Gene, Accession # | [NLK], Gene ID: 445934, NCBI: AAF86838.1 |
Catalog # | MBS2518111 |
Price | $150, $225, $360 |
Order / More Info | NLK Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |