Mouse RAGE Antibody from MYBIOSOURCE INC.
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| Edit | |
|---|---|
| Antigenic Specificity | Mouse RAGE |
| Clone | [2B65] |
| Host Species | Rat |
| Reactive Species | mouse |
| Isotype | IgG2 |
| Format | Protein G purified |
| Size | 0.1 mg |
| Concentration | n/a |
| Applications | Western Blot (WB), Immunohistochemistry (IHC) - Formalin |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | This antibody detects mouse RAGE in Western blotting. Advanced glycation endproducts (AGE) are adducts formed by the nonenzymatic glycation or oxidation of macromolecules. AGE forms during aging and its formation is accelerated under pathophysiologic states such as diabetes, Alzheimer's disease, renal failure and immune/inflammatory disorders. Receptor for Advanced Glycation Endoproducts (RAGE), named for its ability to bind AGE, is a multiligand receptor belonging the immunoglobulin (Ig) superfamily. Besides AGE, RAGE binds amyloid betapeptide, S100/calgranulin family proteins, high mobility group B1 (HMGB1, also know as amphoterin) and leukocyte integrins. The mouse RAGE gene encodes a 403 amino acid (aa) residue type I transmembrane glyc |
| Immunogen | Antibody Generation: This antibody was produced from a hybridoma (mouse myeloma fused with spleen cells from a rat immunized with purified mouse recombinant RAGE extracellular domain. The IgG2 fraction of the culture supernatant was purified by Protein A/G affinity chromatography. Antigen: Recombinant mouse RAGE extracellular domain |
| Other Names | [mouse Receptor for Advanced Glycation End Products [RAGE] (#2B65)], [Ager; Ager; RAGE; RAGE] |
| Gene, Accession # | [RAGE], Gene ID: 11596, NCBI: NP_031451.2, UniProt: O35444 |
| Catalog # | MBS690938 |
| Price | $490 |
| Order / More Info | Mouse RAGE Antibody from MYBIOSOURCE INC. |
| Product Specific References | n/a |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
sales@mybiosource.com
http://www.MyBioSource.com
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