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Antigenic Specificity | CAGE-1 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | immunogen affinity purified |
Size | 0.03 mL, 0.1 mL, 0.2 mL |
Concentration | 1 mg/ml |
Applications | Western Blot (WB), Immunohistochemistry (IHC) Paraffin, ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: CAGE-1 Polyclonal Antibody detects endogenous levels of CAGE-1 protein. CAGE (cancer-associated gene protein), also known as DEAD box protien 53 (DDX53) or DEAD box protein CAGE, belongs to the DEAD box helicase family. It contains one helicase ATP-binding domain, one helicase C-terminal domain and one KH domain. CAGE localizes to the nucleus and, in normal adult tissues, is exclusively expressed in testis but it has also been found in a wide variety of cancer tissues and cell lines. Overexpression of CAGE leads to the activation of FAK, ERK and p38 MAPK along with a reduction in reactive oxygen species (ROS). It is also responsible for inducing catalase activity and therefore enhancing cell motility. This suggests that CAGE ma |
Immunogen | Immunogen: Synthesized peptide derived from the C-terminal region of human CAGE-1 at AA range: 680-760 |
Other Names | [Rabbit CAGE-1; CAGE1; CTAG3; Cancer-associated gene 1 protein; CAGE-1; Cancer/testis antigen 3; CT3] |
Gene, Accession # | [CAGE-1], Gene ID: 285782, NCBI: NP_001164164.1, UniProt: Q8TC20 |
Catalog # | MBS9701558 |
Price | $130, $220, $325 |
Order / More Info | CAGE-1 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |