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Antigenic Specificity | CD25 |
Clone | monoclonal |
Host Species | Mouse |
Reactive Species | human |
Isotype | IgG1 |
Format | immunogen affinity purified |
Size | 0.03 mL, 0.1 mL, 0.2 mL |
Concentration | 1 mg/ml |
Applications | Immunohistochemistry (IHC) Paraffin |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | The antibody detects endogenous human CD25 protein. The interleukin 2 (IL2) receptor alpha (IL2RA) and beta (IL2RB) chains, together with the common gamma chain (IL2RG), constitute the high-affinity IL2 receptor. Homodimeric alpha chains (IL2RA) result in low-affinity receptor, while homodimeric beta (IL2RB) chains produce a medium-affinity receptor. Normally an integral-membrane protein, soluble IL2RA has been isolated and determined to result from extracellular proteolyisis. Alternately-spliced IL2RA mRNAs have been isolated, but the significance of each is presently unknown. Mutations in IL2RA are associated with interleukin 2 receptor alpha deficiency. |
Immunogen | Immunogen: Synthetic Peptide |
Other Names | [Mouse CD25; IL2RA; Interleukin-2 receptor subunit alpha; IL-2 receptor subunit alpha; IL-2-RA; IL-2R subunit alpha; IL2-RA; TAC antigen; p55; CD25] |
Gene, Accession # | [CD25], Gene ID: 3559, NCBI: NP_000408.1, UniProt: P01589 |
Catalog # | MBS9700389 |
Price | $130, $220, $325 |
Order / More Info | CD25 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |