CRLF1 Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityCRLF1
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman, mouse, rat
Isotypen/a
Formatpeptide affinity purified
Size0.1 mL, 0.2 mL
Concentration1mg/ml
ApplicationsWestern Blot (WB), Immunohistochemistry (IHC), ELISA (EIA)
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DescriptionSpecificity: CRLF1 antibody detects endogenous levels of total CRLF1. Function: Cytokine receptor subunit, possibly playing a regulatory role in the immune system and during fetal development. May be involved in nervous system development.Subunit Structure: Forms covalently linked di-and tetramers. Forms a heteromeric complex with cardiotrophin-like cytokine (CLC); the CRLF1/CLC complex is a ligand for the ciliary neurotrophic factor receptor (CNTFR).Similarity: The WSXWS motif appears to be necessary for proper protein folding and thereby efficient intracellular transport and cell-surface receptor binding. Belongs to the type I cytokine receptor family. Type 3 subfamily.
ImmunogenImmunogen: A synthesized peptide derived from human CRLF1 Subcellular Location: Secreted Tissue Specificity: Highest levels of expression observed in spleen, thymus, lymph node, appendix, bone marrow, stomach, placenta, heart, thyroid and ovary. Strongly expressed also in fetal lung. Predicted Cross Reactivity: Pig, Bovine, Sheep, Dog, Chicken Similarity: Pig (91%), Bovine (91%), Sheep (91%), Dog (91%), Chicken (91%)
Other Names[CISS 1; CISS; CISS1; class I cytokine receptor; CLF 1; CLF; CLF1; CRLF 1; Cytokine like factor 1; Cytokine receptor like factor 1; cytokine type 1 receptor CRLP 1; NR 6; NR6; ZcytoR 5; ZcytoR5]
Gene, Accession #[CRLF1], Gene ID: 9244, NCBI: NP_004741.1, UniProt: O75462
Catalog #MBS9609247
Price$240, $280
Order / More InfoCRLF1 Antibody from MYBIOSOURCE INC.
Product Specific Referencesn/a
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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