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Antigenic Specificity | CRLF1 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | peptide affinity purified |
Size | 0.1 mL, 0.2 mL |
Concentration | 1mg/ml |
Applications | Western Blot (WB), Immunohistochemistry (IHC), ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: CRLF1 antibody detects endogenous levels of total CRLF1. Function: Cytokine receptor subunit, possibly playing a regulatory role in the immune system and during fetal development. May be involved in nervous system development.Subunit Structure: Forms covalently linked di-and tetramers. Forms a heteromeric complex with cardiotrophin-like cytokine (CLC); the CRLF1/CLC complex is a ligand for the ciliary neurotrophic factor receptor (CNTFR).Similarity: The WSXWS motif appears to be necessary for proper protein folding and thereby efficient intracellular transport and cell-surface receptor binding. Belongs to the type I cytokine receptor family. Type 3 subfamily. |
Immunogen | Immunogen: A synthesized peptide derived from human CRLF1 Subcellular Location: Secreted Tissue Specificity: Highest levels of expression observed in spleen, thymus, lymph node, appendix, bone marrow, stomach, placenta, heart, thyroid and ovary. Strongly expressed also in fetal lung. Predicted Cross Reactivity: Pig, Bovine, Sheep, Dog, Chicken Similarity: Pig (91%), Bovine (91%), Sheep (91%), Dog (91%), Chicken (91%) |
Other Names | [CISS 1; CISS; CISS1; class I cytokine receptor; CLF 1; CLF; CLF1; CRLF 1; Cytokine like factor 1; Cytokine receptor like factor 1; cytokine type 1 receptor CRLP 1; NR 6; NR6; ZcytoR 5; ZcytoR5] |
Gene, Accession # | [CRLF1], Gene ID: 9244, NCBI: NP_004741.1, UniProt: O75462 |
Catalog # | MBS9609247 |
Price | $240, $280 |
Order / More Info | CRLF1 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |