MSH2 (Center) Antibody from MYBIOSOURCE INC.
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| Antigenic Specificity | MSH2 (Center) |
| Clone | [1184CT1.3.2] |
| Host Species | Mouse |
| Reactive Species | human |
| Isotype | IgG1 |
| Format | unconjugated |
| Size | 0.08 mL, 0.4 mL |
| Concentration | vial concentration: 0.5 |
| Applications | Western Blot (WB), ELISA (EIA) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Specificity: Purified His-tagged MSH2 protein was used to produced this monoclonal antibody. Component of the post-replicative DNA mismatch repair system (MMR). Forms two different heterodimers: MutS alpha (MSH2-MSH6 heterodimer) and MutS beta (MSH2-MSH3 heterodimer) which binds to DNA mismatches thereby initiating DNA repair. When bound, heterodimers bend the DNA helix and shields approximately 20 base pairs. MutS alpha recognizes single base mismatches and dinucleotide insertion-deletion loops (IDL) in the DNA. MutS beta recognizes larger insertion-deletion loops up to 13 nucleotides long. After mismatch binding, MutS alpha or beta forms a ternary complex with the MutL alpha heterodimer, which is thought to be responsible for directing th |
| Immunogen | n/a |
| Other Names | [DNA mismatch repair protein Msh2; hMSH2; MutS protein homolog 2; MSH2] |
| Gene, Accession # | [MSH2], Gene ID: 4436, NCBI: NP_000242.1, UniProt: P43246 |
| Catalog # | MBS9200032 |
| Price | $165, $370 |
| Order / More Info | MSH2 (Center) Antibody from MYBIOSOURCE INC. |
| Product Specific References | Leonardis D., et al. Hum. Genet. 119:675-675(2006). Fishel R., et al. Cell 75:1027-1038(1993). Fishel R., et al. Cell 77:167-167(1994). Leach F.S., et al. Cell 75:1215-1225(1993). Kolodner R.D., et al. Genomics 24:516-526(1994). |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
sales@mybiosource.com
http://www.MyBioSource.com
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