Collagen IV Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityCollagen IV
Clone[3G3]
Host SpeciesMouse
Reactive Specieshuman
IsotypeIgG1
Formatimmunogen affinity purified
Size0.1 mg
Concentrationn/a
ApplicationsWestern Blot (WB), Immunohistochemistry (IHC) Paraffin
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DescriptionSpecificity: No cross reactivity with other proteins. Description: Mouse IgG monoclonal antibody for Collagen IV detection. Tested with WB, IHC-P in Human.Background: COL4A1, also known as ICH or Collagen alpha-1 (IV), is a protein that in humans is encoded by the COL4A1 gene. It is mapped to 13q34. This gene encodes the major type IV alpha collagen chain of basement membranes. Like the other members of the type IV collagen gene family, this gene is organized in a head-to-head conformation with another type IV collagen gene so that each gene pair shares a common promoter. COL4A1 binds to alpha-1/beta-1 integrin and inhibits migration, proliferation, and tube formation by endothelial cells. It is also a potential therapeutic candidate fo
ImmunogenImmunogen: E Coli-derived human Collagen IV recombinant protein (Position: G1445-T1669). Human Collagen IV shares 97% amino acid (aa) sequence identity with mouse Collagen IV.
Other Names[Collagen alpha-1 (IV) chain; Arresten; COL4A1; Collagen, type IV, alpha 1]
Gene, Accession #[COL4A1], Gene ID: 1282, NCBI: NP_001290039.1, UniProt: P02462
Catalog #MBS1752097
Price$315
Order / More InfoCollagen IV Antibody from MYBIOSOURCE INC.
Product Specific References1. Soininen R, Haka-Risku T, Prockop DJ, Tryggvason K (Jan 1988). Complete primary structure of the alpha 1-chain of human basement membrane (type IV) collagen. FEBS Lett 225 (1-2): 188-94. 2. Plaisier E, Gribouval O, Alamowitch S et al. (2007). COL4A1 mutations and hereditary angiopathy, nephropathy, aneurysms, and muscle cramps. N. Engl. J. Med. 357 (26): 2687-2695. 3. Wang, X., Harris, R. E., Bayston, L. J., Ashe, H. L. Type IV collagens regulate BMP signalling in Drosophila. Nature 455: 72-77, 2008.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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