ARHGDIA Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityARHGDIA
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman, mouse, rat
Isotypen/a
Formataffinity purified
Size0.1 mL
Concentrationn/a
ApplicationsWestern Blot (WB), Immunofluorescence (IF)
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DescriptionControls Rho proteins homeostasis. Regulates the GDP/GTP exchange reaction of the Rho proteins by inhibiting the dissociation of GDP from them, and the subsequent binding of GTP to them. Retains Rho proteins such as CDC42, RAC1 and RHOA in an inactive cytosolic pool, regulating their stability and protecting them from degradation. Actively involved in the recycling and distribution of activated Rho GTPases in the cell, mediates extraction from membranes of both inactive and activated molecules due its exceptionally high affinity for prenylated forms. Through the modulation of Rho proteins, may play a role in cell motility regulation. In glioma cells, inhibits cell migration and invasion by mediating the signals of SEMA5A and PLXNB3 that lea
ImmunogenImmunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 1-204 of human ARHGDIA (NP 001172006.1).
Other Names[GDIA1; NPHS8; RHOGDI; RHOGDI-1; HEL-S-47e]
Gene, Accession #[ARHGDIA], Gene ID: 396, NCBI: NP_001172006.1, UniProt: P52565
Catalog #MBS8549044
Price$280
Order / More InfoARHGDIA Antibody from MYBIOSOURCE INC.
Product Specific Referencesn/a
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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