FAK (Phospho-Ser843) Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityFAK (Phospho-Ser843)
Clonepolyclonal
Host SpeciesRabbit
Reactive Speciesn/a
Isotypen/a
Formatepitope affinity purified
Size0.05 mL, 0.1 mL
Concentration1.0 mg/ml
ApplicationsWestern Blot (WB)
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DescriptionThe antibody detects endogenous level of FAK only when phosphorylated at serine 843. Non-receptor protein-tyrosine kinase implicated in signaling pathways involved in cell motility, proliferation and apoptosis. Activated by tyrosine-phosphorylation in response to either integrin clustering induced by cell adhesion or antibody cross-linking, or via G-protein coupled receptor (GPCR) occupancy by ligands such as bombesin or lysophosphatidic acid, or via LDL receptor occupancy. Plays a potential role in oncogenic transformations resulting in increased kinase activity.
ImmunogenImmunogen Type: Peptide-KLH Immunogen Description: Peptide sequence around phosphorylation site of serine843(R-G-S(p)-I-D) derived from Human FAK.
Other Names[FADK 1; FAK1; Focal adhesion kinase 1; PTK2; pp125FAK]
Gene, Accession #[FAK], Gene ID: 5747, NCBI: NP_001186578.1, UniProt: Q05397
Catalog #MBS9403939
Price$200, $255
Order / More InfoFAK (Phospho-Ser843) Antibody from MYBIOSOURCE INC.
Product Specific Referencesn/a
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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