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Antigenic Specificity | KPNA3 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | peptide affinity purified |
Size | 0.1 mL |
Concentration | n/a |
Applications | ELISA (EIA), Western Blot (WB), Immunocytochemistry (ICC) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Karyopherin, a cytosolic and heterodimeric protein complex consisting of alpha and beta subunits, is responsible for targeting proteins with nuclear localization signals to the nuclear pore complex by an energy requiring, Ran-dependent mechanism. The alpha subunit and imported substrate enter the nucleus and accumulate in the nucleoplasm, while the beta subunit accumulates at the NPC. KPNA3, the alpha subunit 3 of karyopherin, is silimar to human KPNA2, suggesting that KPNA3 may be involved in the nuclear transport system. It is ubiquitously expressed and recent studies have shown that human KPNA3 may be associated with schizophrenia. |
Immunogen | Immunogen Type: Peptide Immunogen Description: Raised against a 14 amino acid peptide near the carboxy end of human KPNA3. |
Other Names | [Karyopherin alpha nucleoprotein interactor 3, importin alpha 4, IPOA4, importin-alpha-Q2, QIP2, SRP4] |
Gene, Accession # | [KPNA3], Gene ID: 3839, NCBI: NP_002258 |
Catalog # | MBS9414775 |
Price | $320 |
Order / More Info | KPNA3 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |