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Antigenic Specificity | ITGB2 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | immunogen affinity purified |
Size | 0.1 mL |
Concentration | 1.0 mg/ml |
Applications | Western Blot (WB), Immunohistochemistry (IHC) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | The antibody detects endogenous level of total ITGB2 protein. In the immune system, integrins have essential roles in leukocyte trafficking and function. These include immune cell attachment to endothelial and antigen-presenting cells, cytotoxicity, and extravasation into tissues (1). Integrin adhesion receptors transduce signals that control complex cell functions which require the regulation of gene expression, such as proliferation, differentiation and survival. Their intracellular domain has no catalytic function, indicating that interaction with other transducing molecules is crucial for integrin-mediated signaling. JAB1 (Jun activation domain-binding protein 1), a coactivator of the c-Jun transcription factor, has been identified as a |
Immunogen | Immunogen Type: Recombinant Protein Immunogen Description: Recombinant protein of human ITGB2. |
Other Names | [ITGB2; CD18; LAD; LCAMB; LFA-1] |
Gene, Accession # | [ITGB2], Gene ID: 3689, NCBI: NP_000202.3, UniProt: P05107 |
Catalog # | MBS9410699 |
Price | $255 |
Order / More Info | ITGB2 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |