Edit |   |
---|---|
Antigenic Specificity | Mouse ICAM-1 |
Clone | [MAB0802] |
Host Species | Rat |
Reactive Species | mouse |
Isotype | IgG2 |
Format | Protein A purified |
Size | 0.1 mg |
Concentration | n/a |
Applications | Immunohistochemistry (IHC) - Paraffin, Flow Cytometry (FC/FACS) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Intercellular adhesion molecule 1 (ICAM-1), also known as CD54, binds the leukocyte integrins LFA-1 and Mac-1. ICAM-1 expression is weak on leukocytes, epithelial and resting endothelial cells, as well as some other cell types, but expression can be stimulated by IFN-gamma, TNF-alpha, IL-1 beta and LPS. Soluble ICAM-1 is found in a biologically active form in serum, probably as a result of proteolytic cleavage from the cell surface. |
Immunogen | Antibody Generation: This antibody was produced from a hybridoma (mouse myeloma fused with spleen cells from a rat immunized with cytokine stimulated mouse endothelial cells. IgG fraction of the culture supernatant was purified by Protein A/G affinity chromatography. ICAM-1, a 95 kDa surface antigen found on endothelial cells, lymphocytes,epithelial cells, dendritic cells, and keratinocytes. ICAM-1 is a ligand for LFA-1 (CD11a/CD18) and MAC-1(CD11b/CD18). Its expression is up regulated upon stim |
Other Names | [mouse ICAM-1], [Icam1; Icam1; CD54; Ly-47; Icam-1; MALA-2; Icam-1; ICAM-1] |
Gene, Accession # | [ICAM-1], Gene ID: 15894, NCBI: NP_034623.1, UniProt: P13597 |
Catalog # | MBS690600 |
Price | $490 |
Order / More Info | Mouse ICAM-1 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |