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Antigenic Specificity | GNB5 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | affinity purified |
Size | 0.1 mL |
Concentration | n/a |
Applications | Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Enhances GTPase-activating protein (GAP) activity of regulator of G protein signaling (RGS) proteins, hence involved in the termination of the signaling initiated by the G protein coupled receptors (GPCRs) by accelerating the GTP hydrolysis on the G-alpha subunits, thereby promoting their inactivation (Probable). Increases RGS9 GTPase-activating protein (GAP) activity, hence contributes to the deactivation of G protein signaling initiated by D2 dopamine receptors (PubMed:27677260). May play an important role in neuronal signaling, including in the parasympathetic, but not sympathetic, control of heart rate. |
Immunogen | Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 1-200 of human GNB5 (NP 006569.1). |
Other Names | [GB5; IDDCA; LADCI] |
Gene, Accession # | [GNB5], Gene ID: 10681, NCBI: NP_006569.1, UniProt: O14775 |
Catalog # | MBS8545387 |
Price | $280 |
Order / More Info | GNB5 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |