CD8a Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityCD8a
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman.
Isotypen/a
Formatunconjugated
Size0.02 mg (With BSA & Azide at 0.2mg/ml), 0.1 mg (With BSA & Azide at 0.2mg/ml), 0.1 mg (Without BSA & Azide at 1mg/ml)
Concentrationn/a
ApplicationsELISA (EIA), Flow Cytometry (FC/FACS), Immunofluorescence (IF), Western Blot (WB), Immunoprecipitation (IP), Immunohistology (IH)
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DescriptionSpecificity: CD8 is a cell surface receptor expressed either as a heterodimer with the CD8 beta chain (CD8 alpha/beta) or as a homodimer (CD8 alpha/alpha). A majority of thymocytes and a subpopulation of mature T cells and NK cell express CD8a. CD8 binds to MHC class 1 and through its association with protein tyrosine kinase p56lck plays a role in T cell development and activation of mature T cells. For mature T-cells, CD4 and CD8 are mutually exclusive, so anti-CD8, generally used in conjunction with anti-CD4. It is a useful marker for distinguishing helper/inducer T-lymphocytes, and most peripheral T-cell lymphomas are CD4+/CD8-. Anaplastic large cell lymphoma is usually CD4+ and CD8-, and in T-lymphoblastic lymphoma/leukemia, CD4 and CD8
ImmunogenImmunogen: Human CD8 recombinant fragment corresponding to aa 200-250 Quantity and Buffer: 0.5 ml at 200ug/ml with BSA and azide
Other Names[CD8 antigen; alpha polypeptide (p32); T8/Leu-2 T-lymphocyte differentiation antigen; Ly3; LYT3; MAL; T-cell surface glycoprotein CD8 alpha chain], [CD8A; CD8A; CD8; MAL; p32; Leu2; MAL]
Gene, Accession #[CD8A], Gene ID: 925, NCBI: NP_001139345.1, UniProt: P01732
Catalog #MBS438436
Price$190, $340, $340
Order / More InfoCD8a Antibody from MYBIOSOURCE INC.
Product Specific References1. Mason DY, et. al. Journal of Clinical Pathology, 1992, 45(12):1084-8.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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