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Antigenic Specificity | HAX1 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | immunogen affinity purified |
Size | 0.1 mL |
Concentration | 1.0 mg/ml |
Applications | Western Blot (WB), Immunohistochemistry (IHC) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | The antibody detects endogenous level of total HAX1 protein. The protein encoded by this gene is known to associate with hematopoietic cell-specific Lyn substrate 1, a substrate of Src family tyrosine kinases. It also interacts with the product of the polycystic kidney disease 2 gene, mutations in which are associated with autosomal-dominant polycystic kidney disease, and with the F-actin-binding protein, cortactin. It was earlier thought that this gene product is mainly localized in the mitochondria, however, recent studies indicate it to be localized in the cell body. Mutations in this gene result in autosomal recessive severe congenital neutropenia, also known as Kostmann disease. Two transcript variants encoding different isoforms have |
Immunogen | Immunogen Type: Recombinant Protein Immunogen Description: Recombinant protein of human HAX1. |
Other Names | [SCN3; HS1BP1; HCLSBP1] |
Gene, Accession # | [HAX1], Gene ID: 10456, NCBI: NP_001018238.1, UniProt: O00165 |
Catalog # | MBS9402211 |
Price | $255 |
Order / More Info | HAX1 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |