Fas-Associated protein with Death Domain, FADD Antibody from MYBIOSOURCE INC.
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| Antigenic Specificity | Fas-Associated protein with Death Domain, FADD |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | mouse |
| Isotype | n/a |
| Format | immunogen affinity purified |
| Size | 0.1 mg |
| Concentration | n/a |
| Applications | Western Blot (WB) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Fas-Associated protein with Death Domain (FADD) is a universal adaptor protein in apoptosis that mediates signaling of all known death domain-containing members of the TNF receptor superfamily.[1] the FADD gene contains 2 exons and spans approximately 3.6 kb, and maps to 11q13.3. It is reported that mammalian cells lacking the death domain-containing protein FADD are defective in intracellular double-stranded RNA (dsRNA)-activated gene expression, including production of type I (alpha/beta) interferons, and are thus very susceptible to viral infection.[2] |
| Immunogen | Immunogen: A synthetic peptide (conjugated with KLH) corresponding to the N-terminal of mouse FADD. |
| Other Names | [Fas-Associated protein with Death Domain; FADD], [FADD; FADD; GIG3; MORT1; MORT1] |
| Gene, Accession # | [FADD], Gene ID: 8772, NCBI: CAG33019.1, UniProt: Q13158 |
| Catalog # | MBS355056 |
| Price | $275 |
| Order / More Info | Fas-Associated protein with Death Domain, FADD Antibody from MYBIOSOURCE INC. |
| Product Specific References | 1. Kabra, N. H., Kang, C., Hsing, L. C., Zhang, J., Winoto, A. T cell-specific FADD-deficient mice: FADD is required for early T cell development. Proc. Nat. Acad. Sci. 98: 6307-6312, 2001. 2. Balachandran, S., Thomas, E., Barber, G. N. A FADD-dependent innate immune mechanism in mammalian cells. Nature 432: 401-405, 2004 |
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