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Antigenic Specificity | SNAP 25, Total |
Clone | [9L651] |
Host Species | Mouse |
Reactive Species | n/a |
Isotype | IgG |
Format | supernatant |
Size | 1 mL |
Concentration | n/a |
Applications | ELISA (EL/EIA), Immunohistochemistry (IHC) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Recognizes both the intact whole form of SNAP 25 and the C. botulinum Toxin A cleaved form of SNAP 25. Has been found to bind to cleaved and uncleaved SNAP 25 aa183-197 by ELISA and cell staining techniques. SNAP 25 (synaptosome-associated protein of 25kD) is a highly conserved protein anchored to the cytosolic face of membranes via palmitoyl side chains in the middle of the molecule. SNAP 25 is the target of Botulinum neurotoxin A and E which cleave off 9 and 26aas, respectively, from the C-terminus. The protein is part of the exocytotic fusion complex (v-SNARE) of neurons where it assembles with syntaxin 1 and synaptobrevin/VAMP. The protein is abundantly localized on the neuronal plasmalemma and on recycling vesicles including synaptic v |
Immunogen | Immunogen: Synthetic peptide corresponding to aa183-197 of analogue SNAP 25. |
Other Names | SNAP 25, Total (Synaptosomal-associated Protein 25, Synaptosomal Associated Protein 25, Synaptosomal-associated 25kD Protein, Synaptosomal-associated Protein 25kDa, SNAP25, SNAP-25, bA416N4.2, dJ1068F16.2, FLJ23079, HGNC: 11132, Resistance to Inhibitors of |
Gene, Accession # | Gene ID: 67474, NCBI: NP_075837.3, UniProt: Q9ERB0 |
Catalog # | MBS605805 |
Price | $890 |
Order / More Info | SNAP 25, Total Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |