Human Serine/threonine-protein kinase PAK 1 Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityHuman Serine/threonine-protein kinase PAK 1
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman
Isotypen/a
Formatantigen affinity purified
Size0.05 mL, 0.1 mL
Concentrationn/a
ApplicationsELISA (EIA), Immunohistochemistry (IHC)
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DescriptionProtein kinase involved in intracellular signaling pathways downstream of integrins and receptor-type kinases that plays an important role in cytoskeleton dynamics, in cell adhesion, migration, proliferation, apoptosis, mitosis, and in vesicle-mediated transport processes. Can directly phosphorylate BAD and protects cells against apoptosis. Activated by interaction with CDC42 and RAC1. Functions as GTPase effector that links the Rho-related GTPases CDC42 and RAC1 to the JNK MAP kinase pathway. Phosphorylates and activates MAP2K1, and thereby mediates activation of downstream MAP kinases. Involved in the reorganization of the actin cytoskeleton, actin stress fibers and of focal adhesion complexes. Phosphorylates the tubulin chaperone TBCB an
ImmunogenImmunogen: Recombinant human Serine/threonine-protein kinase PAK 1 protein(1-240aa) Santa Cruz Alternative: Potential replacement for Santa Cruz Biotechnology antibody catalog# sc-882 / sc-881 / sc-11394 / sc-48826
Other Names[Alpha-PAK; p21-activated kinase 1; PAK-1; p65-PAK; PAK1], [PAK1; PAK1; PAKalpha; PAK-1]
Gene, Accession #[PAK1], Gene ID: 5058, NCBI: NP_001122092.1, UniProt: Q13153
Catalog #MBS1499509
Price$120, $160
Order / More InfoHuman Serine/threonine-protein kinase PAK 1 Antibody from MYBIOSOURCE INC.
Product Specific Referencesn/a
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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