CD163, NT Antibody from MYBIOSOURCE INC.
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| Antigenic Specificity | CD163, NT |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human |
| Isotype | n/a |
| Format | ammonium sulfate precipitate |
| Size | 0.2 mL |
| Concentration | 2.04 mg/mL |
| Applications | ELISA (EL/EIA), Western Blot (WB), Immunohistochemistry (IHC). Other applications have not been tested. |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Recognizes human CD163. CD163 is an acute phase-regulated receptor involved in clearance and endocytosis of hemoglobin/haptoglobin complexes by macrophages and may thereby protect tissues from free hemoglobin-mediated oxidative damage. The protein may play a role in the uptake and recycling of iron, via endocytosis of hemoglobin/haptoglobin and subsequent breakdown of heme. It binds hemoglobin/haptoglobin complexes in a calcium-dependent and pH-dependent manner. And it exhibits a higher affinity for complexes of hemoglobin and multimeric haptoglobin of HP*1F phenotype than for complexes of hemoglobin and dimeric haptoglobin of HP*1S phenotype. It also induces a cascade of intracellular signals that involves tyrosine kinase-dependent calcium |
| Immunogen | Immunogen: KLH-conjugated synthetic peptide mapping to a fragement of residues within amino acids 245-274 in the N-terminal region of human CD163. |
| Other Names | CD163, NT (CD163, M130, Scavenger receptor cysteine-rich type 1 protein M130, Hemoglobin scavenger receptor, CD163, Soluble CD163) |
| Gene, Accession # | Gene ID: 9332, NCBI: CAB45233.1, UniProt: Q86VB7 |
| Catalog # | MBS6007064 |
| Price | $610 |
| Order / More Info | CD163, NT Antibody from MYBIOSOURCE INC. |
| Product Specific References | n/a |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
sales@mybiosource.com
http://www.MyBioSource.com
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