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Antigenic Specificity | PBX1 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | peroxidase (HRP) conjugate |
Size | 0.05 mg, 0.1 mg |
Concentration | n/a |
Applications | ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Binds the sequence 5'-ATCAATCAA-3'. Acts as a transcriptional activator of PF4 in complex with MEIS1. Converted into a potent transcriptional activator by the (1; 19) translocation. May have a role in steroidogenesis and, subsequently, sexual development and differentiation. Isoform PBX1b as part of a PDX1:PBX1b:MEIS2b complex in pancreatic acinar cells is involved in the transcriptional activation of the ELA1 enhancer; the complex binds to the enhancer B element and cooperates with the transcription factor 1 complex (PTF1) bound to the enhancer A element. Probably in complex with MEIS2, is involved in transcriptional regulation by KLF4. Acts as a transcriptional activator of NKX2-5 and a transcriptional repressor of CDKN2B. Together with N |
Immunogen | Immunogen: Recombinant Human Pre-B-cell leukemia transcription factor 1 protein (315-430AA) |
Other Names | [Pre-B-cell leukemia transcription factor 1; Homeobox protein PBX1; Homeobox protein PRL; PBX1; PRL] |
Gene, Accession # | [PBX1], Gene ID: 5087, NCBI: NP_001191892.1, UniProt: P40424 |
Catalog # | MBS7105822 |
Price | $160, $235 |
Order / More Info | PBX1 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |