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Antigenic Specificity | LDL Receptor, |
Clone | polyclonal |
Host Species | n/a |
Reactive Species | human, mouse |
Isotype | n/a |
Format | unconjugated |
Size | 0.1 mL |
Concentration | n/a |
Applications | Immunohistochemistry (IHC), Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | The low density lipoprotein (LDL) receptor system coordinates the metabolism of cholesterol, an essential component of the plasma membrane of all mammalian cells. Study of this system has led to an enhanced understanding of the cellular basis of cholesterol homeostasis. It has also brought into focus an important mechanism of metabolic regulation--the process of receptor-mediated endocytosis (1). Data suggest that the juxtamembranous region of the cytoplasmic domain participates in protein:protein interactions that allow the low density lipoprotein receptor to cluster in coated pits (2). It has been shown that the family of LDL receptors may serve as viral receptors. Endocytosis of the Flaviviridae viruses, hepatitis C virus, GB virus C/hep |
Immunogen | Immunogen: Synthetic peptide made to an internal portion of the human protein (within residues 500-550). [Swiss-Prot# P01130] |
Other Names | [low-density lipoprotein receptor isoform 1; Low-density lipoprotein receptor; low-density lipoprotein receptor; low density lipoprotein receptor], [LDLR; LDLR; FH; FHC; LDLCQ2; LDL receptor] |
Gene, Accession # | [LDL], Gene ID: 3949, NCBI: NP_000518.1 |
Catalog # | MBS555118 |
Price | $395 |
Order / More Info | LDL Receptor, Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |