alpha-SMA Antibody from MYBIOSOURCE INC.
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|---|---|
| Antigenic Specificity | alpha-SMA |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human, mouse, rat |
| Isotype | n/a |
| Format | peptide affinity purified |
| Size | 0.1 mL, 0.2 mL |
| Concentration | 1mg/ml |
| Applications | Western Blot (WB), Immunohistochemisty (IHC), Immunoflurescene (IF), Immunocytochemistry (ICC), Immunoprecipitation (IP), ELISA (EIA) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Specificity: alpha-SMA antibody detects endogenous levels of alpha-SMA. Description: Defects in ACTA2 are the cause of aortic aneurysm familial thoracic type 6 (AAT6) [MIM:611788]. AATs are characterized by permanent dilation of the thoracic aorta usually due to degenerative changes in the aortic wall. They are primarily associated with a characteristic histologic appearance known as 'medial necrosis' or 'Erdheim cystic medial necrosis' in which there is degeneration and fragmentation of elastic fibers, loss of smooth muscle cells, and an accumulation of basophilic ground substance.Function: Actins are highly conserved proteins that are involved in various types of cell motility and are ubiquitously expressed in all eukaryotic cells. |
| Immunogen | Immunogen: Synthetic peptide corresponding to N terminal residues of Human alpha smooth muscle Actin. Subcellular Location: Cytoplasm > Cytoskeleton. Tissue Specificity: Up-regulated in response to enterovirus 71 (EV71) infection. Predicted Cross Reactivity: Pig, Bovine, Horse, Sheep, Rabbit, Dog, Chicken Similarity: Pig (100%), Bovine (100%), Horse (100%), Sheep (100%), Rabbit (100%), Dog (100%), Chicken (100%) |
| Other Names | [a actin; AAT6; ACTA_HUMAN; ACTA2; Actin alpha 2 smooth muscle aorta; Actin aortic smooth muscle; Actin, aortic smooth muscle; ACTSA; ACTVS; Alpha 2 actin; Alpha actin 2; Alpha cardiac actin; Alpha-actin-2; Cell growth inhibiting gene 46 protein; Cell growth-inhibiting gene 46 protein; GIG46; Growth inhibiting gene 46; MYMY5] |
| Gene, Accession # | [ACTA2], Gene ID: 59, NCBI: NP_001135417.1, UniProt: P62736 |
| Catalog # | MBS9600621 |
| Price | $240, $280 |
| Order / More Info | alpha-SMA Antibody from MYBIOSOURCE INC. |
| Product Specific References | Qiu H, Wu H, Ma J, Cao H, Huang L, Qiu W, Peng Y, Ding C; Journal: Naunyn Schmiedebergs Arch Pharmacol. DL-3-n-Butylphthalide reduces atrial fibrillation susceptibility by inhibiting atrial structural remodeling in rats with heart failure. Zhao S, Gao Y, Xia X, Che Y, Wang Y, Liu H, Sun Y, Ren W, Han W, Yang J, Lei L; Journal: Microb Pathog. TGF-beta1 promotes Staphylococcus aureus adhesion to and invasion into bovine mammary fibroblasts via the ERK pathway. Xiaojun W, Yan L, Hong X, Xianghong Z, Shifeng L, Dingjie X, Xuemin G, Lijuan Z, Bonan Z, Zhongqiu W, Ruimin W, Brann D, Fang Y; Journal: Sci Rep. Acetylated a-Tubulin Regulated by N-Acetyl-Seryl-Aspartyl-Lysyl-Proline(Ac-SDKP) Exerts the Anti-fibrotic Effect in Rat Lung Fibrosis Induced by Silica. Li XH, Xiao T, Yang JH, Qin Y, Gao JJ, Liu HJ, Zhou HG; Journal: Respir Res. Parthenolide attenuated bleomycin-induced pulmonary fibrosis via the NF-kB/Snail signaling pathway. Liu D, Pan J, Zhao D, Liu F; Journal: Am J Transl Res. MicroRNA-223 inhibits deposition of the extracellular matrix by airway smooth muscle cells through targeting IGF-1R in the PI3K/Akt pathway. |
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MYBIOSOURCE INC.
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