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Antigenic Specificity | TNFRSF1B |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | affinity purified |
Size | 0.1 mg |
Concentration | 1mg/ml |
Applications | Western Blot (WB), Immunohistochemistry (IHC) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: Western blot analysis of 293 cell and MCF7 cell lysate using TNFRSF1B antibody. TNF-+/- is an important cytokine produced by numerous cell types including neutrophils, activated lymphoctyes, macrophages an NK cells. It plays a critical role in inflammatory responses and in apoptosis (1). TNF-+/- exists as a membrane-anchored and soluble form, both of which show biological activity. Response to TNF-+/- is mediated through two receptors, TNF-R1, which is widely expressed, and TNF-R2, which is expressed mainly in immune and endothelial cells (2). Antagonists to TNF-+/- have been validated as therapeutic targets for rheumatoid arthritis and other immune disorders (3). The two receptors for TNF-+/-, TNF-R1 (55 kDa) and TNF-R2 (75 kD |
Immunogen | Immunogen: Recombinant protein of human TNFRSF1B |
Other Names | [tumor necrosis factor receptor superfamily member 1B; Tumor necrosis factor receptor superfamily member 1B; tumor necrosis factor receptor superfamily member 1B; TNF receptor superfamily member 1B; Tumor necrosis factor receptor 2; TNF-R2], [TNFRSF1B; TNFRSF1B; p75; TBPII; TNFBR; TNFR2; CD120b; TNFR1B; TNFR80; TNF-R75; p75TNFR; TNF-R-II; TNFBR; TNFR2; TNF-R2; TNF-RII; TNFR-II] |
Gene, Accession # | [TNFRSF1B], Gene ID: 7133, NCBI: NP_001057.1, UniProt: P20333 |
Catalog # | MBS419533 |
Price | $385 |
Order / More Info | TNFRSF1B Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |