NMDA RECEPTOR NR2B (pTyr1472) Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityNMDA RECEPTOR NR2B (pTyr1472)
Clonepolyclonal
Host SpeciesRabbit
Reactive Speciesbovine (expected from sequence), chicken (expected from sequence), dog (expected from sequence), human (expected from sequence), monkey (expected from sequence), mouse (expected from sequence), zebrafish (expected from sequence)
Isotypen/a
Formatunconjugated
Size0.1 mL
Concentrationn/a
ApplicationsWestern Blot (WB)*
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DescriptionThis item specifically recognises the 180kDa NR2B subunit of the NMDA (N-methyl-D-aspartate) receptor when phosphorylated at Tyr1472. Receptors for NMDA belong to a group of ionotropic glutamate receptors which play a key role in the mediation of glutamate neurotransmission within the mammalian central nervous system (CNS), including involvement in memory and learning processes. Several antagonists and agonists of NMDA receptors (NMDAR) have been identified, including the glutamate analogue Homoquinolinic acid, which displays a higher affinity for NR2B-containing NMDAR. Properties of NMDAR include modulation by glycine, inhibition by Zn2+, voltage-dependent Mg2+ blockade and high Ca2+ permeability. The involvement of NMDAR in the CNS has be
ImmunogenImmunogen: Synthetic phosphopeptide corresponding to an amino acid sequence within the NR2B subunit of the NMDA receptor, which includes phosphorylated Tyr1472. Buffer Solution: 10mM HEPES pH7.5. Antiserum Preparation: Antisera to NMDA receptor NR2B subunit were raised by repeated immunisations of rabbits with highly purified antigen. Purified IgG prepared by affinity chromatography. Target Species: Rat
Other Names[glutamate receptor ionotropic, NMDA 2B; Glutamate receptor ionotropic, NMDA 2B; glutamate receptor ionotropic, NMDA 2B; N-methyl D-aspartate receptor subtype 2B; NMDAR2B; NR2B; glutamate [NMDA] receptor subunit epsilon-2; glutamate receptor, ionotropic, NMDA2B; glutamate receptor, ionotropic, N-methyl D-aspartate 2B; Glutamate [NMDA] receptor subunit epsilon-2; N-methyl D-aspartate receptor subtype 2B; NMDAR2B; NR2B], [Grin2b; Grin2b; GluN2B; GluN2B; NMDAR2B; NR2B]
Gene, Accession #[NMDA], Gene ID: 24410, NCBI: NP_036706.1, UniProt: Q00960
Catalog #MBS221313
Price$550
Order / More InfoNMDA RECEPTOR NR2B (pTyr1472) Antibody from MYBIOSOURCE INC.
Product Specific Referencesn/a
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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