PSEN1 Antibody from MYBIOSOURCE INC.
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|---|---|
| Antigenic Specificity | PSEN1 |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human, mouse, rat |
| Isotype | n/a |
| Format | affinity purified |
| Size | 0.1 mL |
| Concentration | n/a |
| Applications | Western Blot (WB), Immunohistochemistry (IHC) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Presenilin 1 and presenilin 2 are transmembrane proteins belonging to the presenilin family. Mutation of presenilin genes has been linked to early onset of Alzheimer disease, probably due to presenilin's associated gamma-secretase activity for amyloid-beta protein processing (1, 2). Endogenous presenilin mainly exists in a heterodimeric complex formed from the endoproteolytically processed amino-terminal (34 kDa) and carboxy-terminal (~20, 22, 23 kDa) fragments (CTF) (2, 3). |
| Immunogen | Immunogen: Recombinant protein of human PSEN1 Storage Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Other Names | [PSEN1; AD3; FAD; PS-1; PS1; S182] |
| Gene, Accession # | [PSEN1], Gene ID: 5663, NCBI: NP_000012.1, UniProt: P49768 |
| Catalog # | MBS8504403 |
| Price | $310 |
| Order / More Info | PSEN1 Antibody from MYBIOSOURCE INC. |
| Product Specific References | 1. Haass, C. and DeStrooper, B. (1999) Science 286, 916-919. 2. Kimberly, W.T. et al. (2000) J. Biol. Chem. 275, 3173-3178. 3. Kim, T.W. et al. (1997) J. Biol. Chem. 272, 11006-11010. |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
sales@mybiosource.com
http://www.MyBioSource.com
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