TLR4 Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityTLR4
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman
Isotypen/a
Formataffinity purified
Size0.1 mg
Concentration0.2 mg/ml
ApplicationsWestern Blot (WB), Flow Cytometry (FC/FACS)
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DescriptionBackground: TLR4 (Toll-like receptor 4) is a mammalain homologue of the Drosophila toll protein. The human TLR4 is a type-1 transmembrane protein containing 799 amino acid residues. The extracellular domain has leucine-rich repeats and the intracellular domain is similar to that of IL-1 receptor. TLR4 is a receptor for lipopolysaccharide (LPS). In mice that are genetically tolerant to endotoxin, mutations have been identified in the intracellular domain of TLR4 that abolish LPS responsiveness. TLR4 uses a mechanism similar to that of the IL-1 receptor for signal transduction that leads to activation of NF-kB.
ImmunogenImmunogen: Recombinant human TLR4
Other Names[ARMD10; CD284; TOLL; hToll; Toll-like receptor 4], [TLR4; TLR4; TOLL; CD284; TLR-4; ARMD10]
Gene, Accession #[TLR4], Gene ID: 7099, NCBI: NP_003257.1, UniProt: O00206
Catalog #MBS840411
Price$305
Order / More InfoTLR4 Antibody from MYBIOSOURCE INC.
Product Specific Referencesn/a
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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