PRKAR1A Antibody from MYBIOSOURCE INC.
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|---|---|
| Antigenic Specificity | PRKAR1A |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human, rat |
| Isotype | n/a |
| Format | immunogen affinity purified |
| Size | 0.1 mg |
| Concentration | n/a |
| Applications | Western Blot (WB), Immunohistochemistry (IHC) Paraffin |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Rabbit IgG polyclonal antibody for cAMP-dependent protein kinase type I-alpha regulatory subunit(PRKAR1A) detection. Background: cAMP-dependent protein kinase type I-alpha regulatory subunit is an enzyme that in humans is encoded by the PRKAR1A gene. This protein encoded by this gene was found to be a tissue-specific extinguisher that down-regulates the expression of seven liver genes in hepatoma x fibroblast hybrids. Mutations in this gene cause Carney complex (CNC). This gene can fuse to the RET protooncogene by gene rearrangement and form the thyroid tumor-specific chimeric oncogene known as PTC2. A nonconventional nuclear localization sequence (NLS) has been found for this protein which suggests a role in DNA replication via the protein |
| Immunogen | Immunogen: E Coli-derived human PRKAR1A recombinant protein (Position: E2-E81). Human PRKAR1A shares 89.9% and 92.4% amino acid (aa) sequence identity with mouse and rat PRKAR1A, respectively. |
| Other Names | [ACRDYS1; ADOHR; CAR; CNC 1; CNC; CNC1; PKA RIA; PKR 1; PKR1; PPNAD 1; PPNAD1; PRKAR 1; PRKAR1; PRKAR1A; TSE 1; TSE1; P10644; cAMP-dependent protein kinase type I-alpha regulatory subunit; protein kinase cAMP-dependent type I regulatory subunit alpha], [PRKAR1A; PRKAR1A; CAR; CNC; CNC1; PKR1; TSE1; ADOHR; PPNAD1; PRKAR1; ACRDYS1; PKR1; PRKAR1; TSE1; TSE1] |
| Gene, Accession # | [PRKAR1A], Gene ID: 5573, NCBI: NP_001263218.1, UniProt: P10644 |
| Catalog # | MBS178619 |
| Price | $315 |
| Order / More Info | PRKAR1A Antibody from MYBIOSOURCE INC. |
| Product Specific References | 1. Entrez Gene: PRKAR1A protein kinase, cAMP-dependent, regulatory, type I, alpha (tissue specific extinguisher 1).2. Scambler P, Oyen O, Wainwright B, Farrall M, Law HY, Estivill X, Sandberg M, Williamson R, Jahnsen T (December 1987). Exclusion of catalytic and regulatory subunits of cAMP-dependent protein kinase as candidate genes for the defect causing cystic fibrosis. Am J Hum Genet. 41 (5): 925-32. |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
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P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
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