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Antigenic Specificity | Phospho-FAK (pTyr 576) |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human; rat; mouse |
Isotype | n/a |
Format | epitope affinity purified |
Size | 0.1 mg |
Concentration | 0.5mg/ml |
Applications | ELISA, Western Blot, Immunohistochemistry |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | This antibody recognizes FAK (pY576) with a phosphorylated site at Tyrosine 576. It does not crossreact with non-phosphospecific peptide. Focal adhesion kinase (FAK) gene encodes a cytoplasmic protein tyrosine kinase which is found concentrated in the focal adhesions that form between cells growing in the presence of extracellular matrix constituents. The encoded protein is a member of the FAK subfamily of protein tyrosine kinase but lacks significant sequence similarity to kinase from other subfamilies. Activation by phosphorylation of Y397, Y576/577 and Y863 of FAK protein may be an important early step in cell growth and intracellular signal transduction pathways triggered in response to certain neural peptides or to cell interactions wi |
Immunogen | n/a |
Other Names | n/a |
Gene, Accession # | [FAK (pY576)] |
Catalog # | MBS462199 |
Price | $275 |
Order / More Info | Phospho-FAK (pTyr 576) Antibody from MYBIOSOURCE INC. |
Product Specific References | Leu TH, et al. Tyr-863 phosphorylation enhances focal adhesion kinase autophosphorylation at Tyr-397. Oncogene. 2002 Oct 10;21 (46):6992-7000. |