BST 2 Antibody from MYBIOSOURCE INC.
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| Antigenic Specificity | BST 2 |
| Clone | [ABM52D8] |
| Host Species | Mouse |
| Reactive Species | rat, mouse, human |
| Isotype | IgG1 kappa |
| Format | Protein G purified |
| Size | 0.1 mg |
| Concentration | n/a |
| Applications | Flow Cytometry (FC/FACS), Western Blot (WB) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | BST2 (Bone Marrow Stromal Antigen 2), a type II transmembrane protein also known as HM1.24/CD317, has been identified to be overexpressed in a variety of cell lines from different cancer types, including multiple myeloma, breast, lung, and kidney cancers. BST2 was discovered as a marker of differentiated B cells and was later rediscovered as a potent antiviral restriction factor with the ability to tether enveloped viruses to the cell membrane of infected cells via its GPI anchor as well as to potently inhibit virus replication in cultured cells and in vivo. It also acts as an innate immune sensor of HIV-1 that elicits an inflammatory response upon exposure. BST2 mediate host immune response by activating NF-KB through interaction with TAK1 |
| Immunogen | Immunogen Information: Full length recombinant protein of BST 2 was used as the immunogen for this antibody. |
| Other Names | [Bone marrow stromal antigen 2; HM1.24 antigen; Tetherin; CD317], [BST2; BST2; CD317; TETHERIN; BST-2] |
| Gene, Accession # | [BST2], Gene ID: 684, NCBI: Q10589.1, UniProt: Q10589 |
| Catalog # | MBS668285 |
| Price | $290 |
| Order / More Info | BST 2 Antibody from MYBIOSOURCE INC. |
| Product Specific References | n/a |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
sales@mybiosource.com
http://www.MyBioSource.com
Profile of MYBIOSOURCE INC.
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