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Antigenic Specificity | GABA A Receptor a 3 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | epitope affinity purified |
Size | 0.05 mL, 0.1 mL |
Concentration | 1.0 mg/ml |
Applications | Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | The antibody detects endogenous level of total GABA A Receptor a3 protein. GABA (g-aminobutyric acid) is the primary inhibitory neurotransmitter in the central nervous system and interacts with three different receptors: GABA(A), GABA(B) and GABA(C) receptor. The ionotropic GABA(A) and GABA(C) receptors are ligand-gated ion channels that produce fast inhibitory synaptic transmission. In contrast, the metabotropic GABA(B) receptor is coupled to G proteins that modulate slow inhibitory synaptic transmission (1). Functional GABA(B) receptors form heterodimers of GABA(B)R1 and GABA(B)R2 where GABA(B)R1 binds the ligand and GABA(B)R2 is the primary G protein contact site (2). Two isoforms of GABA(B)R1 have been cloned: GABA(B)R1a is a 130 kD pro |
Immunogen | Immunogen Type: Peptide-KLH Immunogen Description: Peptide sequence around aa. 33~37(R-R-Q-E-P)derived from Rat GABA A Receptor a3. |
Other Names | [Gamma-aminobutyric acid receptor subunit alpha-3; Gabra3] |
Gene, Accession # | [GABA A], Gene ID: 24947, NCBI: P20236.1, UniProt: P20236 |
Catalog # | MBS9402376 |
Price | $200, $255 |
Order / More Info | GABA A Receptor a 3 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |