PRKAR1A Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityPRKAR1A
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman, mouse, rat
Isotypen/a
Formatimmunogen affinity purified
Size0.1 mL
Concentration1.0 mg/ml
ApplicationsWestern Blot (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)
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DescriptionThe antibody detects endogenous level of total PRKAR1A protein. The second messenger cyclic AMP (cAMP) activates cAMP-dependent protein kinase (PKA or cAPK) in mammalian cells and controls many cellular mechanisms such as gene transcription, ion transport, and protein phosphorylation (1). Inactive PKA is a heterotetramer composed of a regulatory subunit (R) dimer and a catalytic subunit (C) dimer. In this inactive state, the pseudosubstrate sequences on the R subunits block the active sites on the C subunits. Three C subunit isoforms (C-a, C-b, and C-g) and two families of regulatory subunits (RI and RII) with distinct cAMP binding properties have been identified. The two R families exist in two isoforms, a and b (RI-a, RI-b, RII-a, and RII
ImmunogenImmunogen Type: Recombinant Protein Immunogen Description: Recombinant protein of human PRKAR1A.
Other Names[PRKAR1A; CAR; CNC; CNC1; DKFZp779L0468]
Gene, Accession #[PRKAR1A], Gene ID: 5573, NCBI: NP_001263218.1, UniProt: P10644
Catalog #MBS9411391
Price$255
Order / More InfoPRKAR1A Antibody from MYBIOSOURCE INC.
Product Specific Referencesn/a
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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