PECAM-1 (Phospho-Tyr713) Antibody from MYBIOSOURCE INC.
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|---|---|
| Antigenic Specificity | PECAM-1 (Phospho-Tyr713) |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human |
| Isotype | n/a |
| Format | epitope affinity purified |
| Size | 0.05 mL, 0.1 mL |
| Concentration | 1.0 mg/ml |
| Applications | Western Blot (WB) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | The antibody detects endogenous level of PECAM-1 only when phosphorylated at tyrosine 713. Induces susceptibility to atherosclerosis By similarity. Cell adhesion molecule which is required for leukocyte transendothelial migration (TEM) under most inflammatory conditions. Tyr-690 plays a critical role in TEM and is required for efficient trafficking of PECAM1 to and from the lateral border recycling compartment (LBRC) and is also essential for the LBRC membrane to be targeted around migrating leukocytes. Prevents phagocyte ingestion of closely apposed viable cells by transmitting 'detachment' signals, and changes function on apoptosis, promoting tethering of dying cells to phagocytes (the encounter of a viable cell with a phagocyte via the h |
| Immunogen | Immunogen Type: Peptide-KLH Immunogen Description: Peptide sequence around phosphorylation site of Tyrosine 713(T-V-Y(p)-S-E) derived from Human PECAM-1. |
| Other Names | [CD31; CD31 antigen; EndoCAM; PEC1; PECAM] |
| Gene, Accession # | [PECAM-1], Gene ID: 5175, NCBI: NP_000433.4, UniProt: P16284 |
| Catalog # | MBS9402771 |
| Price | $200, $255 |
| Order / More Info | PECAM-1 (Phospho-Tyr713) Antibody from MYBIOSOURCE INC. |
| Product Specific References | n/a |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
sales@mybiosource.com
http://www.MyBioSource.com
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