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Antigenic Specificity | EIF2AK3 |
Clone | polyclonal |
Host Species | Mouse |
Reactive Species | human |
Isotype | n/a |
Format | unconjugated |
Size | 0.1 mg |
Concentration | n/a |
Applications | Western Blot (WB), ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | The protein encoded by this gene phosphorylates the alpha subunit of eukaryotic translation-initiation factor 2 (EIF2), leading to its inactivation, and thus to a rapid reduction of translational initiation and repression of global protein synthesis. It is a type I membrane protein located in the endoplasmic reticulum (ER), where it is induced by ER stress caused by malfolded proteins. Mutations in this gene are associated with Wolcott-Rallison syndrome. |
Immunogen | Immunogen: Purified recombinant fragment of human EIF2AK3 expressed in E. Coli. |
Other Names | [PAX8], [EIF2AK3; EIF2AK3; PEK; WRS; PERK; PEK; PERK; HsPEK] |
Gene, Accession # | [EIF2AK3], Gene ID: 9451, NCBI: NP_004827.4, UniProt: Q9NZJ5 |
Catalog # | MBS850887 |
Price | $280 |
Order / More Info | EIF2AK3 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |