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Antigenic Specificity | FADD |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, rat, monkey |
Isotype | n/a |
Format | Peptide Affinity purified |
Size | 0.05 mg, 0.2 mg |
Concentration | n/a |
Applications | Immunocytochemistry (ICC), Immunohistochemistry (IHC) Paraffin, Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Recognizes human, rat, and monkey FADD. Detects a band of ~28kDa by Western blot. Fas-associating death domain containing protein (FADD)/MORT1 serves as a signal transducer of Fas-induced apoptosis. Through its amino-terminal death effector domain (DED), FADD binds to cytosolic proteins such as TRADD, a cytosolic death domaincontaining protein that asssociates with the cytosolic portion of TNF receptor, or MACH/FLICE/caspase-8, a protease with sequence homology to ICE-CED-3 protease family, in order to transduce the death signal. |
Immunogen | Immunogen: Synthetic peptide corresponding to a portion of human FADD. |
Other Names | [MORT1; Fas (TNFRSF6)-associated via death domain], [FADD; FADD; GIG3; MORT1; MORT1] |
Gene, Accession # | [FADD], Gene ID: 8772, NCBI: Q13158.1, UniProt: Q13158 |
Catalog # | MBS565236 |
Price | $295, $510 |
Order / More Info | FADD Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |