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Antigenic Specificity | SNX27 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | Protein G purified |
Size | 0.05 mg, 0.1 mg |
Concentration | n/a |
Applications | ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Involved in the retrograde transport from endosome to plasma membrane, a trafficking pathway that promotes the recycling of internalized transmembrane proteins. Following internalization, endocytosed transmembrane proteins are delivered to early endosomes and recycled to the plasma membrane instead of being degraded in lysosomes. SNX27 specifically binds and directs sorting of a subset of transmembrane proteins containing a PDZ-binding motif at the C-terminus: following interaction with target transmembrane proteins, associates with the retromer complex, preventing entry into the lysosomal pathway, and promotes retromer-tubule based plasma membrane recycling. SNX27 also binds with the WASH complex. Interacts with membranes containing phosph |
Immunogen | Immunogen: Recombinant Human Sorting nexin-27 protein (458-497AA) |
Other Names | [Sorting nexin-27; SNX27; KIAA0488; My014] |
Gene, Accession # | [SNX27], Gene ID: 81609, NCBI: NP_001317652.1, UniProt: Q96L92 |
Catalog # | MBS7050855 |
Price | $160, $235 |
Order / More Info | SNX27 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |