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Antigenic Specificity | Human Protein S100-A9 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | caprylic acid ammonium sulfate precipitate |
Size | 0.05 mg, 0.1 mg |
Concentration | n/a |
Applications | ELISA (EIA), Immunohistochemistry (IHC) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | S100A9 is a calcium- and zinc-binding protein which plays a prominent role in the regulation of inflammatory processes and immune response. It can induce neutrophil chemotaxis, adhesion, can increase the bactericidal activity of neutrophils by promoting phagocytosis via activation of SYK, PI3K/AKT, and ERK1/2 and can induce degranulation of neutrophils by a MAPK-dependent mechanism. Predominantly found as calprotectin (S100A8/A9) which has a wide plethora of intra- and extracellular functions. The intracellular functions include: facilitating leukocyte arachidonic acid trafficking and metabolism, modulation of the tubulin-dependent cytoskeleton during migration of phagocytes and activation of the neutrophilic NADPH-oxidase. Activates NADPH- |
Immunogen | Immunogen: Recombinant human Protein S100-A9 protein |
Other Names | [Calgranulin-B Calprotectin L1H subunit Leukocyte L1 complex heavy chain Migration inhibitory factor-related protein 14 S100 calcium-binding protein A9 S100A9 CAGB; CFAG; MRP14] |
Gene, Accession # | [S100A9], Gene ID: 6280, NCBI: NP_002956.1, UniProt: P06702 |
Catalog # | MBS7001469 |
Price | $160, $235 |
Order / More Info | Human Protein S100-A9 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |