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Antigenic Specificity | SMYD3 |
Clone | [1B5C10] |
Host Species | Mouse |
Reactive Species | human |
Isotype | IgG1 |
Format | Protein G purified |
Size | 0.06 mL, 0.12 mL, 0.2 mL |
Concentration | 1mg/mL |
Applications | Western Blot (WB), Immunohistochemistry (IHC), ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | SMYD3, also name as ZMYND1 and ZNFN3A1, belongs to the histone-lysine methyltransferase family.It is a histone methyltransferase that plays an important role in transcriptional regulation in human carcinogenesis. It can specifically methylate histone H3 at lysine 4 and activate the transcription of a set of downstream genes, including several oncogenes (e.g., N-myc, CrkL, Wnt10b, RIZ and hTERT) and genes involved in the control of cell cycle. It plays an important role in transcriptional activation as a member of an RNA polymerase complex. SMYD3 is frequently overexpressed in different types of cancer cells. It functions as a coactivator of Era and potentiates Era activity in response to ligand. SMYD3 as a new coactivator for ER-mediated t |
Immunogen | Immunogen: Fusion Protein of SMYD3 Buffer: PBS with 0.02% sodium azide, 50% glycerol, PH7.3 Conjugation: Unconjugated |
Other Names | [bA74P14.1; FLJ21080; SMYD3; ZMYND1; ZNFN3A1] |
Gene, Accession # | [SMYD3], Gene ID: 64754, NCBI: BC031010, UniProt: Q9H7B4 |
Catalog # | MBS2549141 |
Price | $220, $290, $435 |
Order / More Info | SMYD3 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |