SETDB1 - N-terminal region Antibody from MYBIOSOURCE INC.

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Antigenic SpecificitySETDB1 - N-terminal region
Clonepolyclonal
Host SpeciesRabbit
Reactive Speciescow, dog, guinea pig, horse, human, rabbit, rat
Isotypen/a
Formataffinity purified
Size0.1 mL
Concentrationn/a
ApplicationsWestern Blot (WB)
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DescriptionThis is a rabbit polyclonal antibody against SETDB1. It was validated on Western BlotTarget Description: SETDB1 is a histone methyltransferase that specifically trimethylates 'Lys-9' of histone H3. H3 'Lys-9' trimethylation represents a specific tag for epigenetic transcriptional repression by recruiting HP1 (CBX1, CBX3 and/or CBX5) proteins to methylated histones. SETDB1 mainly functions in euchromatin regions, thereby playing a central role in the silencing of euchromatic genes. H3 'Lys-9' trimethylation is coordinated with DNA methylation. It probably forms a complex with MBD1 and ATF7IP that represses transcription and couples DNA methylation and histone 'Lys-9' trimethylation. Its activity is dependent on MBD1 and is heritably
ImmunogenImmunogen: The immunogen is a synthetic peptide directed towards the N-terminal region of Human SETDB1
Other Names[Histone-lysine N-methyltransferase SETDB1; Histone-lysine N-methyltransferase SETDB1; histone-lysine N-methyltransferase SETDB1; SET domain bifurcated histone lysine methyltransferase 1; ERG-associated protein with SET domain; ESET; Histone H3-K9 methyltransferase 4; H3-K9-HMTase 4; Lysine N-methyltransferase 1E; SET domain bifurcated 1]
Gene, Accession #[SETDB1], Gene ID: 9869, NCBI: Q15047.1, UniProt: Q15047
Catalog #MBS3204388
Price$335
Order / More InfoSETDB1 - N-terminal region Antibody from MYBIOSOURCE INC.
Product Specific Referencesn/a
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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